In 2004, Fontana et al. published data from a study of 18 individuals who had been on CR for an average of 6 years and 18 age-matched healthy individuals on typical American diets. The study took one ...
In 1934, Mary Crowell and Clive McCay of Cornell University observed that laboratory rats fed a severely reduced calorie diet while maintaining micronutrient levels resulted in life spans of up to twi ...
Caloric restriction (CR), or calorie restriction, is a dietary regimen that is based on low calorie intake. "Low" can be defined relative to the subject's previous intake before intentionally restrict ...