Management of AIS is currently limited to symptomatic management; no method is currently available to correct the malfunctioning androgen receptor proteins produced by AR gene mutations. Areas of mana ...
AIS is broken down into three classes based on phenotype: complete androgen insensitivity syndrome (CAIS), partial androgen insensitivity syndrome (PAIS), and mild androgen insensitivity syndrome (MAI ...
Sex determination and differentiation is generalized with chromosomal sex during fertilization. At early stages, phenotypic sex does not match chromosomal sex—until later during intrauterine developm ...
DSDs are medical conditions involving the way the reproductive system develops from infancy (and before birth) through young adulthood. There are several types of DSDs and their effect on the external ...
SRY may have arisen from a gene duplication of the X chromosome bound gene SOX3, a member of the Sox family. This duplication occurred after the split between monotremes and therians. Monotremes lack ...
The following systematic list gender taxonomy illustrates the kinds of diversity that have been studied and reported in medical literature. It is placed in roughly chronological order of biological an ...
The Y chromosome was identified as a sex-determining chromosome by Nettie Stevens at Bryn Mawr College in 1905 during a study of the mealworm Tenebrio molitor. Edmund Beecher Wilson discovered the sam ...
The X chromosome in humans spans more than 153 million base pairs (the building material of DNA). It represents about 2000 out of 20,000 - 25,000 genes. Each person normally has one pair of sex chromo ...
Topoisomerases are enzymes with both nuclease and ligase activity. These proteins change the amount of supercoiling in DNA. Some of these enzymes work by cutting the DNA helix and allowing one section ...
In a DNA double helix, each type of nucleobase on one strand bonds with just one type of nucleobase on the other strand. This is called complementary base pairing. Here, purines form hydrogen bonds to ...
XX/XY sex chromosomesDrosophila sex-chromosomesMain article: XY sex-determination systemThe XX/XY sex-determination system is the most familiar, as it is found in humans. In the system, females have t ...
Many terms have been used to describe atypical sexual interests, and there remains debate regarding technical accuracy and perceptions of stigma. Sexologist John Money popularized the term paraphilia ...
Because there is significant variation among people who identify as asexual, asexuality can encompass broad definitions. Researchers generally define asexuality as the lack of sexual attraction or the ...
Many non-human animal species exhibit bisexual behavior. Examples of mammals that display such behavior include the bonobo (formerly known as the pygmy chimpanzee), orca, and the bottlenose dolphin. E ...
Sexual orientation, identity, behaviorMain articles: Sexual orientation, Sexual identity and Human sexual activitySee also: Situational sexual behaviorBisexuality is the romantic or sexual attraction ...
